Adult ADHD Diagnosis Linked to Increased Dementia Risk, Study Suggests

Recent research indicates that adults diagnosed with attention deficit hyperactivity disorder (ADHD) may face a heightened risk of developing dementia later in life. While the study does not conclusively establish a cause-and-effect relationship, it underscores the importance of further exploration into potential connections and the potential impact of ADHD medications on dementia risk.


Key Takeaways:

  • Adults diagnosed with ADHD may have a higher risk of dementia.
  • The study does not confirm if the link is cause and effect.
  • ADHD medications might influence the risk, requiring more research.
  • The study emphasizes the importance of consent in replicating an individual’s likeness using AI.
  • The Screen Actors Guildā€American Federation of Television and Radio Artists (SAG-AFTRA) supports the bill.
  • The Motion Picture Association (MPA) stresses the importance of First Amendment rights.

The research, based on the medical records of over 100,000 individuals, revealed that those diagnosed with ADHD in adulthood had almost triple the risk of a later dementia diagnosis. The study’s findings suggest that processes associated with adult ADHD might diminish the brain’s ability to compensate for other processes occurring later in life, such as neurodegeneration or altered brain blood flow.

Dr. Stephen Levine, the study’s lead author from the University of Haifa, noted that the findings align with the primary result that adult ADHD might increase dementia risk. However, there’s also mild evidence suggesting reverse causation.

The research team analyzed electronic health records from Meuhedet Healthcare Services, a nonprofit health maintenance organization in Israel. They excluded individuals with pre-existing ADHD or dementia diagnoses. The study commenced in January 2003, tracking records until February 2020, or until participants either left the HMO, were diagnosed with dementia, or passed away.

Of the 109,218 participants, 730 were diagnosed with adult ADHD during the study. Among these, 96 (13%) were also diagnosed with dementia. In comparison, only 7% of those without an ADHD diagnosis were diagnosed with dementia. After accounting for various factors, including age, sex, socioeconomic status, and health conditions, the risk of dementia diagnosis was found to be 2.77 times higher among those diagnosed with adult ADHD.

Interestingly, the study also hinted that ADHD medications might alter this risk. The team found no clear link between ADHD and dementia among those exposed to psychostimulant medication, a common treatment for ADHD. However, this observation warrants further investigation.

While the study provides valuable insights, it has its limitations. It does not confirm if the observed link extends to childhood ADHD, nor does it conclusively establish a cause-and-effect relationship. Prof. Roxana O Carare from the University of Southampton suggested that future studies could investigate whether disturbances in neurotransmitter levels in the brain, as seen in ADHD, are linked to an increased dementia risk.

Prof. Chris Hollis from the University of Nottingham highlighted potential confounding factors. He pointed out that adults who seek an ADHD diagnosis are also more likely to be assessed for other cognitive or neuropsychiatric conditions, including dementia. He emphasized the need for further research to validate the link and determine if ADHD treatment could mitigate the potential risk.

Henry Shelford, CEO of ADHD UK, emphasized the urgent need for more in-depth research on ADHD and its secondary effects. He noted the ongoing struggle for ADHD recognition in the UK and the importance of understanding its broader implications.

In the age of rapid technological advancements, especially in the realm of Artificial Intelligence, the ethical considerations surrounding the use of AI in replicating human likenesses and the potential health implications of conditions like ADHD are becoming increasingly crucial. As we continue to navigate these complex intersections of health, technology, and ethics, studies like this one provide valuable insights and pave the way for informed decision-making.